MCB 403
Cell & Membrane Physiology

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About this Course	Personnel	Class Schedule and TimeTable Note there are wait lists for both sections. And two pending sections, Wed afternoon and Thursday moring.
Computer Resources Nature encyclopedia of Life Sciences Compass (where you can see your grades)	UIUC's Writers Workshop FASEB Journal Information for Authors 1) How to write a scientific Paper (Bates College) 2) How to write a scientific Paper again (George Mason Univ) How to use Graphs & Tables in your papers Reference Guide	403/404 Main Page
Course Documents Syllabus Computer Resources Animal use in this course	Announcements   Lab and Lecture Times Annoucement	Molecular & Integrative Physiology Page MCB 401 Home page
Server access via Mac OSX Server access via Windows Using Life Sci File Servers Remember for off campus server access you will need VPN

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About the Course

This course is an upper level physiology laboratory course. We have approached teaching advanced physiology in the laboratory from a unique perspective, that of a research lab(within time (4 hour lab/week) and monetary constraints). Students are expected to take the initiative to prepare for the lab and when creating their lab reports, to do so in the form of a journal article. This course takes considerable time and effort. The reward is the ability to think independently, troubleshoot, and learn current techniques that are useful in research, graduate and medical school.

• Orientation
• Abstract Guidelines
• Oral Report Guidelines

All documents are provided in Adobe Acrobat (pdf) format.

For further information on this course e-mail me at malmgren@uiuc.edu..

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Syllabus

Lab #		Dates		R	O	A	Lect.	Sol	Description and Notes
Orientation.		08-22-2011					Orientation Slides - 2011 Orientation Slides - 2010		Orientation. Lectures will begin with a Orientation lecture on Monday August 22 in 165 Noyes Lab. Followed by Lab on Tuesday, August 23 at 1 pm for Section 2/B or Thursday, August 25 at 1 pm for Section 4/D in 230 Burrill Hall. Pending Sections 3/C and 6/E will be notified if meeting Using Life Sci File Servers Section 2/B Lab Slides Section 4/D Lab Policies Are you a Technologically Illiterate Student?
Lab # 1		08-29-2011		R1			Slides #1-2011 Slides #1-2010	1S	Equipment Orientation. Ion Analyzer Manual Microfuge manual Server access via Mac OSX Server access via Windows
Lab # 2		09-05-2011				A1	Slides #2-2011 Slides #2-2010	2S	Red Blood Cell Permeability Monday, Sept 5 is Labor Day so lecture will be on Tuesday, Sept 6 from 11am - 12 noon in 393 Bevier Hall. Ethylene Glycol data sheet Image of 2006 of NaCl Series in Procedure I after 6 hours Cellular Volume Control Aquaporins Mechanisms Why do we produce Heparin & where?
Lab # 3		09-19-2011				A2	Slides #3-2011 Slides #3-2010	3S	Intra & Extra-cellular [Na] & [K] levels. THE EFFECT OF SODIUM IONS ON THE ELECTRICAL ACTIVITY OF THE GIANT AXON OF THE SQUID BY A. L. HODGKIN AND B. KATZ Bovine Hemoglobin Values Banked Blood loses needed chemical for RBC passage Nernst calculator MicroCentrifuge Manual Hemoglobin Meter Manual Video on using the Hb Meter
Lab # 4		09-26-2011				A3	Slides #4-2011 Slides #4-2010	4S	Diffusion Potential Universal Gas Constant Faraday's Constant Chart - A Tutorial
Lab # 5		10-3-2011		R2			Slides #5-2011 Slides #5-2010	old 5S new 5S	Active Sodium Transport The Two-Membrane Model of Epithelial Transport: Koefoed-Johnsen and Ussing (1958) Frog Skin calculations Voltage, Current, and/or Resistance Calculator
Lab # 6		10-10-2011			O1		Slides #6-2011 Slides #6-2010	6S	Organelles I "How a Painkiller Turns Liver-killer" in Science 10-11-02 Acetaminophen references Glutathione references The First Synthetic Organelle
Lab # 7		10-17-2011			O1		Slides #7-2011 Slides #7-2010	7S	Organelles II Body/Organ Info from last week Bradford Assay Standard Curve Sect 2 "Modulation of Acetaminophen-Induced Hepatotoxicity by the Xenobiotic Receptor CAR" in Science 298 (5592): 422 Liver damage References
Lab # 8		10-24-2011					Slides #8-2011 Slides #8-2010	8S	Respiration I: Yeast Leland Clark Clark Electrode
		10-25-2011							Midterm I Covers Labs 1 through 7. Tues. October 25, 2011 at 7-9 p.m. Location: 124 Burrill Hall No programable calculators Midterm #1 Key Scores
Lab # 9		10-31-2011		R3			Slides #9-2011 Slides #9-2010	9S	Respiration II: Heart Particles Can ATP Synthase run in reverse?
Lab #10		11-07-2011			O2		Slides #10-2011 Slides #10-2010	10S	Neurophysiology Scope Guide Data from White Board 403-2011
Lab #11		11-14-2011		R4			Slides #11-2011 Slides #11-2010	11S	Neuro-Muscle Physiology Structure of Curare Structure of Gallamine
		11-21-2011							Thanksgiving Week No Lecture or Laboratory.
Lab #12		11-28-2011				A4	Slides #12-2011 Slides #12-2010	12S	Muscle Physiology Sunmmation - Incomplete Tetanus - Tetanus Excitation-Contraction coupling Muscle Organization Sliding Filament Theory
		12-06-2011							Midterm II & Final Covers Labs 8 through 12 & Comprehensive Final. Tues. December 6, 2011 at 7 - 10 p.m. Location: 124 Burrill Hall No programable calculators Midterm #2 & Final Key Scores

Key

• R: Reports
• O: Oral Report
• A: Abstract
• Lect.: Lecture
• Sol: Solutions.

 

Personnel		Office	Phone #	E-mail
Carl Malmgren, Lab Director	Office	220 Burrill Hall	(217) 244-6574	malmgren@uiuc.edu
	Departmental	524 Burrill Hall	(217) 333-1735
	Lab	230 Burrill Hall	(217) 333-7029
TA
Jenny Kim	Office	230A Burrill Hall	(217) 333-7029	jskim3@illinois.edu

   

 

Computer Resources

Microcomputer sites.

There are a number of sites across campus. Check with CITES for a current directory and available hardware and software. You can log into our servers from these sites. Remember that there are a number of different ways to put together a Macintosh system. This can result in screens that are smaller than those we have in the lab and less memory.

Data Acquisition

PowerLab is data recording solution for the life sciences. It features real-time display of experimental data, quick data manipulation, on-line computations, convenient file storage and report-standard data presentation.

With the Macintosh operating system (Mac OS) interface, MacLabs is a fast, multi-channel data recorder, recording up to 200,000 samples per second, that is intuitive to use.

Animal Use

Some animal dissection and the use of animal tissues are required in this course. Alternatives are not available. Inquires concerning the use of dissection and animal tissues can be directed to the instructor or Head of the Department.

Copyright © 2011 Carl Malmgren

All rights Reserved

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Carl H. Malmgren, II malmgren@uiuc.edu Date Last Modified: 8-19-2011