MCB 403
Cell & Membrane Physiology

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About this Course	Personnel	Class Schedule
Computer Resources "Nature" encyclopedia of Life Sciences Compass (where you can see your grades)	UIUC's Writers Workshop FASEB Journal Information for Authors 1) How to write a scientific Paper (Bates College) 2) How to write a scientific Paper again (George Mason Univ) How to use Graphs & Tables in your papers Reference Guide	403/404 Main Page
Course Documents Syllabus Computer Resources Animal use in this course	Announcements We are using ICES On-Line for our course evaluations	Molecular & Integrative Physiology Page MCB 401 Home page
Server access via Mac OSX Server access via Windows Using Life Sci File Servers Remember for off campus server access you will need VPN	Midterm #1 Key Scores	Midterm #2 & Final Key Scores

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About the Course

This course is an upper level physiology laboratory course. We have approached teaching advanced physiology in the laboratory from a unique perspective, that of a research lab(within time (4 hour lab/week) and monetary constraints). Students are expected to take the initiative to prepare for the lab and when creating their lab reports, to do so in the form of a journal article. This course takes considerable time and effort. The reward is the ability to think independently, troubleshoot, and learn current techniques that are useful in research, graduate and medical school.

• Orientation
• Abstract Guidelines
• Oral Report Guidelines

All documents are provided in Adobe Acrobat (pdf) format. Download it from Adobe's server.

For further information on this course e-mail me at malmgren@uiuc.edu..

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Syllabus

Lab #		Dates		R	O	A	Lect.	Sol	Description and Notes
Orientation.		08-24-2009					Orientation Slides - 2009		Orientation. Lectures will begin with a Orientation lecture on Monday August 24 in 163 Noyes Lab. Followed by Lab on Tuesday, August 25 at 1 pm for Section 2 or Thursday, August 27 at 1 pm for Section 4 in 230 Burrill Hall Using Life Sci File Servers Section 2 & 4 Lab Policies Section 2 & 4 Orientation Slides
Lab # 1		08-31-2009		R1			Slides #1-2009 Slides #1-2008	1S	Equipment Orientation. Ion Analyzer Manual Server access via Mac OSX Server access via Windows
Lab # 2		09-07-2009				A1	Slides #2-2009 Slides #2-2008	2S	Red Blood Cell Permeability Monday, Sept 7 is Labor Day so lecture will be on Tuesday, Sept 8 from 12 - 1 pm Location: 144 Lomis Lab. Ethylene Glycol data sheet Image of 2006 of NaCl Series in Procedure I after 6 hours Cellular Volume Control Aquaporins Mechanisms
Lab # 3		09-14-2009				A2	Slides #3-2009 Slides #3-2008	3S	Intra & Extra-cellular [Na] & [K] levels. Bovine Hemoglobin Values Banked Blood loses needed chemical for RBC passage Nernst calculator New Data Sheets MicroCentrifuge Manual Hemoglobin Meter Manual Hemoglobin Test Card Manual
Lab # 4		09-22-2009				A3	Slides #4-2009 Slides #4-2008	4S	Diffusion Potential Universal Gas Constant Faraday's Constant Chart - A Tutorial
Lab # 5		9-29-2009		R2			Slides #5-2009 Slides #5-2008	5S	Active Sodium Transport   Frog Skin calculations
Lab # 6		10-5-2009			O1		Slides #6-2009 Slides #6-2008	6S	Organelles I "How a Painkiller Turns Liver-killer" in Science 10-11-02 Told you so!! Acetaminophen references Glutathione references The First Synthetic Organelle
Lab # 7		10-12-2009			O1		Slides #7-2009 Slides #7-2008	7S	Organelles II "Modulation of Acetaminophen-Induced Hepatotoxicity by the Xenobiotic Receptor CAR" in Science 298 (5592): 422 Liver damage References
Lab # 8		10-19-2009					Slides #8-2009 Slides #8-2008	8S	Respiration I: Yeast Leland Clark Clark Electrode
		10-20-2009							Midterm I Covers Labs 1 through 7. Tues. October 20, 7-9 p.m. Location: 124 Burrill Hall No programable Calculators Midterm #1 Key
Lab # 9		10-26-2009		R3			Slides #9-2009 Slides #9-2008	9S	Respiration II: Heart Particles Can ATP Synthase run in reverse?
Lab #10		11-02-2009			O2		Slides #10-2009 Slides #10-2008	10S	Neurophysiology
Lab #11		11-09-2009		R4			Slides #11-2009 Slides #11-2008	11S	Neuro-Muscle Physiology Structure of Curare Structure of Gallamine
Lab #12		11-17-2009				A4	Slides #12-2009 Slides #12-2008	12S	Muscle Physiology Sunmmation - Incomplete Tetanus - Tetanus Excitation-Contraction coupling Muscle Organization Sliding Filament Theory
		11-24-2009							Thanksgiving Week No Lecture or Laboratory.
		12-01-2009							Midterm II & Final Covers Labs 8 through 12 & Comprehensive Final. Tues. December 1, from 7-10 p.m. Location: 124 Burrill Hall No programable Calculators Midterm #2 & Final Key

Key

• R: Reports
• O: Oral Report
• A: Abstract
• Lect.: Lecture
• Sol: Solutions.

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Personnel

Name	Office	Phone #	E-Mail
Carl Malmgren, Lab Director	220 Burrill Hall 524 Burrill Hall 230 Burrill Hall	(217) 244-6574 (Office) (217) 333-1735 (Departmental) (217) 333-7029 (Lab)	malmgren@uiuc.edu
Yang Yu, TA	230a Burrill Hall	333-2819	yangyu1@illinois.edu

Computer Resources

Microcomputer sites.

There are a number of sites across campus. Check with CITES for a current directory and available hardware and software. You can log into our servers from these sites. Remember that there are a number of different ways to put together a Macintosh system. This can result in screens that are smaller than those we have in the lab and less memory.

Data Acquisition

PowerLab is data recording solution for the life sciences. It features real-time display of experimental data, quick data manipulation, on-line computations, convenient file storage and report-standard data presentation.

With the Macintosh operating system (Mac OS) interface, MacLabs is a fast, multi-channel data recorder, recording up to 200,000 samples per second, that is intuitive to use.

Animal Use

Some animal dissection and the use of animal tissues are required in this course. Alternatives are not available. Inquires concerning the use of dissection and animal tissues can be directed to the instructor or Head of the Department.

403/404 Main Page

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Carl H. Malmgren, II
malmgren@uiuc.edu
Date Last Modified: 11/19/09